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Clarazole (Ketoconazole)
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Ketoconazole

Clarazole is only found in individuals that have used or taken this drug. It is a broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. [PubChem]Clarazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability. Other mechanisms may involve the inhibition of endogenous respiration, interaction with membrane phospholipids, inhibition of yeast transformation to mycelial forms, inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis. Clarazole can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Clarazole is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth.

Clarazole cream is used to treat:

  • Athlete's foot (tinea pedis; ringworm of the foot);
  • Ringworm of the body (tinea corporis);
  • Ringworm of the groin (tinea cruris; jock itch);
  • Seborrheic dermatitis;
  • "Sun fungus" (tinea versicolor; pityriasis versicolor); and
  • Yeast infection of the skin (cutaneous candidiasis).

Clarazole foam or gel is used to treat seborrheic dermatitis (scaly areas on your skin or scalp).

Clarazole 1% shampoo is used to treat dandruff.

Clarazole 2% shampoo is used to treat "sun fungus" (tinea versicolor; pityriasis versicolor).

This medicine may also be used for other fungus infections of the skin as determined by your doctor.

Most forms of this medicine are available only with your doctor's prescription. Some forms are available without a prescription. However, your doctor may have special instructions on the proper use for your medical condition.

This product is available in the following dosage forms:

  • Shampoo
  • Cream
  • Foam
  • Gel/Jelly

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Clinical trials now demonstrate that it is possible to enhance immune reconstitution after SCT with cytokines or infusions of ex vivo costimulated expanded T cells. A customized distractor was used for distraction of the coronal suture at a rate of 0.4 mm/day for 8 days. Purification and cDNA cloning of Xenopus laevis skin peptidylhydroxyglycine N-C lyase, catalyzing the second reaction of C-terminal alpha-amidation. Strengthening district health systems in Ghana: the experience of Ejisu District. A novel algorithm with improved robustness to measurement errors is presented by combining a windowed Fourier transformation with wavelet-based differentiation.

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: Robotic mitral valve (MV) repairs are performed at many institutions. Significantly greater venous distensibility was found during the first half compared with the second half of the menstrual cycle. Corrigendum: Cocaine exposure impairs multilineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor. Early studies showed that the polyamines are closely connected to the proliferation of animal cells. We found that there is indeed more than one stable ion conformation for each of the investigated ions.

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Also, in the in vitro fertilization cycles, the ovarian response to ovulation induction was statistically significantly reduced in cystectomized ovaries as compared with coagulated ovaries. Male Sprague-Dawley rats were anesthetized with sodium pentobarbital.

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In addition to being the first study reporting the nature of a physiological signal triggering sporulation in clostridia, these findings have relevance for the development of antisporulation drugs to prevent or treat CPE-mediated GI diseases in humans. The MoS2 flake-based sensor detected a NO2 concentration as low as 1.2 ppm and exhibited excellent gas-sensing stability. AMPK is a serine/threonine protein kinase family and we recently identified a novel member, ARK5. Abnormal specificity of chymotrypsin in the digestion of citraconylated A-protein was observed.

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Using the modified Schirmer test to measure mouth dryness: a preliminary study. Logistic regression modelling was used to identify the independent contribution of these substructures. Nuclear run-on transcription showed that this induction occurred at the transcriptional level. Although 2-mercaptomethyl-3-guanidinoethylthiopropanoic acid (MGTA, a carboxypeptidase inhibitor) alone did not alter bradykinin reactivity, MGTA in the presence of both phosphoramidon and captopril significantly potentiated bradykinin-induced airway reactivity.

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Hence the combined health effects associated with the pollutants were estimated by aggregating the pollutants with different weights. More on the dynamics of dust generation: the effects of mixing and sanding chrysotile, calcium carbonate, and other components on the characteristics of joint-compound dusts.

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Given the same eGFR level, urine albumin might be a better risk marker to predict progression of CKD and future development of cardiovascular diseases (CVDs). As a result, the thiopental sodium dose that reliably induced any nonpremedicated patient decreased from 6 mg/kg (ED99 of 5.57 mg/kg) to 2.5 mg/kg (ED99 of 2.37 mg/kg). Besides that, tissue and protein arrays and other proteomic approaches have been also used.

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Previous studies have shown that IFN-gamma, TNF-alpha and NOS-2, but not B cells, are crucial for host defense against primary systemic infection with the attenuated live vaccine strain (LVS) of Francisella tularensis. Exercise and executive function in individuals with chronic stroke: a pilot study.

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Spreading depolarization is induced experimentally by various noxious conditions including chemicals such as potassium, glutamate, inhibitors of the sodium pump, status epilepticus, hypoxia, hypoglycemia and ischemia, but it can can also invade healthy, naive tissue. Ornithobacterium rhinotracheale and Mycoplasma synoviae in broiler chickens in Jordan. Description and validation of a questionnaire for the detection of meteoropathy and meteorosensitivity: the METEO-Q. Influence of species, physico-chemical properties of insulin and physiological factors. A wide variety of artifacts may be found when monitoring the ECG in a neonatal intensive care unit.

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On thorough review of literature, it was found that this is only the second male infant reported with isolated thoracoschisis. We assessed the perceived workload with the NASA Task Load Index in twenty-one subjects who were exposed to two different feedback tasks in a cross-over design: (i) brain-robot interface (BRI) with haptic/proprioceptive feedback of sensorimotor oscillations related to motor imagery, and (ii) control of neuromuscular activity with feedback of the electromyography (EMG) of the same hand. Incarcerated women and depression: a primer for the primary care provider. NB survivors require intensive interdisciplinary medical care of paediatric oncologist, neurologist, and nephrologist. The gradient approach was useful in identifying the industrial effluent as a point source for bioavailable chemicals.

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Acellular ECM sheets were fabricated from human adipose tissue through successive physical and chemical treatments: homogenization, centrifugation, casting, freeze-drying and sodium dodecyl sulfate treatment. Quantification of SC by means of a 96-well microplate-based colorimetric method is feasible and shortens the time of analysis. It was concluded that enhanced communication and partnership building improves comprehension and compliance with dental treatment.

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The mice were immunized with VP2-70 vector, VP2-70-LTB fused vector, or VP2-70 vector plus LTB vector, respectively. Necrotic changes in metastatic lymph nodes have not been previously analyzed in English literature.

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In response to general growth factor stimulation, Akt signaling is attenuated in merlin RNA interference-suppressed human arachnoid and Schwann cells by mechanisms mediated by hyperactive mTORC1 and impaired mTORC2. Oxidation of low density lipoproteins is an initial step of atherogenesis that generates pro-inflammatory phospholipids, including platelet-activating factor (PAF). microPET was performed on mice bearing EMT-6 tumors and the images were analyzed for tumor-to-muscle uptake ratios.

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This study compared 12-month CD4 and viral load outcomes in HIV-infected children and adolescents with virological failure, managed with four treatment switch strategies. The substantial contribution of health state to the VAS indicates that it is a valid measure of health-related quality of life (HRQoL) across population groups.

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Effect of lead acetate on the spontaneous activity of young rats. At higher power, sequential phonon assisted tunneling processes excite the double dot in a highly nonequilibrium state. Early postoperative evaluation of secondary bone grafting into the alveolar cleft and its effects on subsequent orthodontic treatment. In a series of previous reports it was established by implementing metabolic flux, NMR/MS, and Northern blot analysis that the glyoxylate shunt, the TCA cycle, and acetate uptake by acetyl-CoA synthetase are more active in Escherichia coli BL21 than in Escherichia coli JM109.

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Important electron-hole interaction effects on the line shape of the optical transitions above the surface-state gap are also found. However, antiviral responses must be tightly regulated in order to prevent uncontrolled production of type I IFN that might have deleterious effects on the host. Coping style as a predictor of compliance with referral to active rehabilitation in whiplash patients. Two of the patients subsequently developed squamous cell carcinoma and eight patients had more than one recurrence. Here we report the identification of mixed lineage kinase domain-like, MLKL, as a key RIP3 downstream component of TNF-induced necrosis.

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(4) In order to eliminate dermatophytes gathered in socks and footwear, simple procedures (washing, bathing with hot water, or wiping with a towel) are all effective. A standardised telephone survey addressing treating ophthalmologists in Germany was used to acquire information in terms of VEGF inhibitors in ophthalmology.

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Impulse-control disorders (ICDs) are becoming more commonly recognized in the Parkinson disease (PD) population. Osteoblastic metastases can be caused by tumor-secreted endothelin-1 (ET-1), but there are a variety of other potential osteoblastic factors. The aetiology and treatment of mental and behavioral disorders among children with Usher syndrome are discussed.

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Baroreflex gain correlated very strongly with base line pulse interval. In the Long motoneuron pool, the amplitude of monosynaptic EPSP was shown to have a close relationship to input resistance. In the adult group, women performed better than men on Speed of Processing and Verbal Learning, and men outperformed women on Attention/Vigilance and Reasoning/Problem Solving tasks. Clinical, light and electron microscopic, histoimmunologic and histoenzymologic study of a case Surfactant protein D (SP-D) plays important roles in innate host defense against influenza A virus (IAV) infection, in part by modifying interactions with neutrophils.

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The chromosomal location of the porcine gene for glucose phosphate isomerase (GPI) was previously mapped to 6p 12----6q21 in the pig karyotype. Accumulating evidence indicates that the mitochondrial cell-death pathway, which involves the release of cytochrome c from mitochondria, participates in neuronal cell death after transient cerebral ischemia. However, challenges continue to surface as faculty struggle to develop and participate in IPE activities while balancing increasing workloads and limited resources, and also trying to keep current in the changing profession-specific accreditation and standards.

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12-Month comorbidity patterns and associated factors in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Assembly of macrocycles by zirconocene-mediated, reversible carbon-carbon bond formation. Using a first-principles approach, we investigate the origin of the fine structure in Si 2p photoelectron spectra at the Si(100)-(2 x 1) surface and at the Si(100)-SiO2 interface. Here we showed that ATP-competitive kinase inhibitors (Torin1 and PP242), which inhibit both mTORC1 and TORC2, also suppressed geroconversion. The purified peptide binds both zinc (two atoms per protein molecule) and iron (as a redox-active iron-sulfur cluster, with four atoms of iron and four atoms of inorganic sulfide per protein molecule).

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Data from all the patients sedated between April and June 2010 were recorded. The present study examines the local strain fields within tendon fascicles subjected to tensile strain in order to determine the mechanisms responsible for fascicle extension. Lipases production by solid-state fermentation: the case of Rhizopus homothallicus in perlite.

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Catalytic methanolysis of hydrazine borane: a new and efficient hydrogen generation system under mild conditions. In conclusion, our data suggest that SNPs in the IL18 gene might be involved in the development of AE by contributing to a functional dysregulation of the IL-18 production in vivo . Familial juvenile polyposis syndrome with a novel SMAD4 germline mutation. Microbiota promoted spontaneous proliferation of T cells by activating dendritic cells to produce interleukin (IL)-6 via a TLR/Myd88-dependent pathway.

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Cough headache and thoracic inlet valvular competence in uremia. The coherent coupling, which is dominated by the bonding and antibonding resonances of the Born-Kuhn type resonators, leads to an extremely steep dispersion for a circularly polarized wave of predefined handedness. In order to ascertain whether characteristic radiographic patterns are seen in patients with pulmonary candidiasis, antemortem radiographic abnormalities were correlated with autopsy findings in 25 immunosuppressed patients who had histoinvasive pulmonary candidiasis. High-performance PdNi alloy structured in situ on monolithic metal foam for coalbed methane deoxygenation via catalytic combustion. We have concluded that general conditions in which the customer is admitted in this scenario contribute to this occurrence and involve mostly, besides the physical space as a therapeutic environment, the improvisation of materials and that the nursing care should be executed in a participatory fashion.

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Think globally, learn locally: Multimedia conferencing between two schools of nursing. MB 3683 was induced by the substrate and stimulated by methionine. Wave intensity analysis of arterial circulations may provide a mechanism to explain diastolic augmentation and systolic unloading of intra-aortic balloon pump counterpulsation.

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Multitrait-multimethod analysis of health-related quality-of-life measures. Further clinical studies are needed to determine how often this approach can safely treat this condition. After exhaustive endocrinologic, radiographic, and physical examinations, the testicular masses were postulated to be active adrenal rest tissue. The author offers two brief clinical examples of working with dissociated self-states. Modifier controls severity of a novel dominant low-frequency MyosinVIIA (MYO7A) auditory mutation.

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Chronic impaired venous outflow from the central nervous system has recently been claimed to be associated with multiple sclerosis (MS) pathology. Findings were compared with a separate IRT model using an alternative coding of symptom criteria that requires distress/impairment to be related to each criterion. In patients who required prolonged mechanical ventilation, there was significant decreased incidence of VAP, less ventilator time, and lower ICU LOS when tracheostomy was performed within 7 days after admission to the SICU. Integrated cerebral protection: combined antegrade and retrograde cerebral perfusion during deep hypothermic circulatory arrest. Quantitative determination of the glutathione, cysteine, and N-acetyl cysteine conjugates of acetaminophen by high-pressure liquid chromatography.

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Comparison of the INR Values Measured by CoaguChek XS Coagulometer and Conventional Laboratory Methods in Patients on VKA Therapy. The PD group had lower proportions of formulaic expressions compared with the AD and HC groups.

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A convenience sample of 144 new ostomy patients was recruited from a large midwest urban level i trauma teaching hospital system. Biomimetic formation of titania thin films: effect of amino acids on the deposition process. Following our previously published methodology, solution-filled mock syringe sources, identical in geometry to the solid (68)Ge epoxy calibration source currently on the market, were prepared using NIST-calibrated solutions of (68)GeCl4 and (18)F-FDG and directly compared in several models of activity calibrators to determine empirically the relative response ratios for these 2 radionuclides.

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Direct dispensing, along with professional management of the rehabilitative process by the otolaryngological-audiological team is advocated on the basis of the positive results to date. The absence of immunoreactive cells or a considerable glial reaction suggest that the device may be considered safe and suitable for further implantation in humans. Here, we analysed the behaviour of a sfp1 null mutant during balanced and transitory states of growth in batch in response to changes in the growth medium carbon sources. The radiological aspect of hypertrophic stenosis of the pylorus in infants

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Current role of cardiac imaging to guide surgical correction of a giant left ventricular pseudoaneurysm. Evaluation of insulin, glucagon, and growth hormone secretion and management with a continuous low-dose insulin infusion. The results provide insight into the molecular basis of the relation between symptomatology of snakebite accidents in humans and the venom composition. The device can therefore be proposed for both diagnosis and screening of colorectal diseases.

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Regional Blood Centres have cefadroxil brand name in pakistan most people the special capabilities and experience to provide the expertise required in tissue banking. The concentration of the Rose Bengal, and the laser fluence were varied and studied. Within the last decade, mass spectrometry analyses of SUMO proteomes have overcome several obstacles, greatly expanding the number of known SUMO target proteins. Phytoestrogens Modulate Breast Cancer Resistance Protein Expression and Function at the Blood-Cerebrospinal Fluid Barrier. Of the 300 systematic reviews, 224 assessed the effectiveness of interventions on health outcomes.

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Intrathecal morphine in an cluvax forte cremated average dose of 0.01 mg/kg was given to 33 patients between ages 11 and 16 years who had spinal arthrodesis for idiopathic scoliosis. Serum HtrA1 is differentially regulated between early-onset and late-onset preeclampsia.

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Here, we ladialis review times investigate the mechanism of the patulin-induced genotoxicity. We investigated the pediatric specificities, psychological experience, and neuropsychologic follow-up. The determination limit of Ru (bpy)3Cl2 x 6H2O was 10(-11) mol x L(-1) and the detection range was from 10(-9) - 10(-5) mol x L(-1) as well as the detection amount of substance was in the range from 0.4 pmol-4 nmol in the optimal reaction conditions with voltage of 1.0 V, current of 1.0 mA, TPrA concentration of 1.5 mol x L(-1) and pH of 7.4. In our study, we investigated the use of an immunostimulatory oligonucleotide (or CpG motif), 1826-ODN to augment the immune response elicited by plasmid DNA vaccine constructs containing Indian subtype C HIV-1 envelope gp120 and gag-protease genes in Balb/c mouse model system.

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MagScrew total artificial heart in vivo performance above 200 beats per minute. The present results show a novel behavior of dynamic-dephasing contrast in poststroke brain tissue, providing data to assess the age of infarction in association to T(2) images. Specific serum IgE is considered as one of the important diagnostic measures in the diagnostic work-up of food allergy. Analysis of both wild-type gabax review sites and desmin-null fibers revealed that the costamere protein talin colocalized with the Z-disk protein alpha-actinin, even at very high strains and stresses.

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The QDs were characterized by X-ray diffraction, high-resolution transmission electron microscopy, UV-Vis absorption and fluorescence spectroscopy. The goal of this study was to describe the relationship between the fetus and the pelvis as the fetus travels through the birth canal, using an open magnetic resonance imaging (MRI) scanner. At concentrations of 0.1 ppm and above, SDS decreases the uptake of thymidine, uridine omeprazole zentiva tablet and phenylalanine into the acid-soluble sponge fraction.

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Spinal muscular atrophy (S.M.A.) type I (Infantile werdnig - Hoffmann Disease) was found in 4:1,600 (1:400) infants of the Egyptian Karaite community. Surgical therapy for hiliar cholangiocarcinoma: analysis of 198 cases. An online tool named GEN-SNiP that identifies variations in a set of test DNA sequences with respect to a standard reference sequence is developed and deployed successfully. Transcranial Doppler ultrasound analysis of resistive index in rostral and caudal cerebral arteries in dogs. We report four topiramate tablets diagnosis definition imported cases of progressive disseminated histoplasmosis (PDH) due to Histoplasma capsulatum variety capsulatum in Human Immunodeficiency Virus-infected patients from West Africa.

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WHO II was the predominant histology and a significant firide 5 mg dosage poor prognostic factor in our study group, indicating different carcinogenetic pathways of NPC between endemic and non-endemic regions. In order to understand the complexities involved in implementing health promotion activities in schools, this study examined experiences of school staff and project officers including barriers, contextual factors and achievements. Impact of different stent alloys on human vascular response to everolimus-eluting stent: an optical coherence tomography study: the OCTEVEREST. A multiplex bead-based suspension array was developed that can be used for the simultaneous detection of antibodies against the surface glycoprotein Gn and the nucleocapsid protein N of Rift Valley fever virus (RVFV) in various animal species. Purposive sampling was used to recruit participants with different socio-demographic characteristics and drug use profiles.

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We present a case of a term infant, with persistent pulmonary hypertension of the newborn with severe pre-ECMO acidosis (arterial blood pH 6.596) in whom venoarterial ECMO was instituted successfully without major circuit or patient-associated complications. Sex differences in drug addiction and response to exercise intervention: From human to animal studies. In Indonesia, Nasopharyngeal Carcinoma (NPC) is the most frequent cancer of the head and neck region. Six-degrees-of-freedom alignment technique that provides diagnostic norfloxacin tz nebenwirkungen magnesium misalignment information. The use of ovarian stimulation, to stimulate a multi-follicular response for assisted reproduction treatments, may force the production of oocytes from follicles that do not reach optimal maturation, possibly yielding oocytes that are not fully competent.

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