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Landel (Efonidipine)

To assess the in-vivo action on the renal microvasculature of the calcium antagonists nifedipine (L-type blocker), Landel (L/T-type blocker), and mibefradil (predominant T-type blocker). Effects of Landel, nicardipine and captopril on proteinuria in aged spontaneously hypertensive rats.

Other names for this medication:
Efonidipine, Landel,

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Features of the metabolic syndrome comprise a major risk for cardiovascular disease and will increase in prevalence with rising childhood obesity. Chemoradiotherapy, including Cisplatin and 5-fluorouracil, appeared to be equal or superior to surgery as salvage therapy in patients with residual disease six weeks after initial nonsurgical treatment.

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Furthermore, in our experimental model of (low flow) intestinal ischemia and reperfusion a significant rise in plasma I-FABP concentrations 15-30 min after clamping of the mesenteric artery was demonstrated. We also calculated the proportion of adolescents with chlamydia that were coinfected with gonorrhea and the proportion of those with gonorrhea that were coinfected with chlamydia. Cognitive mapping deficits in schizophrenia: Evidence from clinical correlates of visuospatial transformations. This suggests that a substantial part of the excess CVD mortality among those with lower education might be explained by conventional risk factors.

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Six cases of upper intestinal gangliocytic paraganglioma, five in the duodenum and one in the jejunum, are reported. Motivated by the AIDS Clinical Trial Group 175 study, where the occurrence time of AIDS was examined only at intermittent clinic visits and the baseline covariate CD4 count was measured with error, we describe a semiparametric maximum likelihood method for analyzing mixed case interval-censored data with mismeasured covariates under the proportional hazards model.

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Further, we discuss risk factors, diagnostic caveats, diagnostic tests and therapy of hemodynamically relevant contrictive pericarditis. This in turn allows more appropriate utilisation of resources, with the potential for both improved clinical outcomes and greater cost-effectiveness.

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Most of the total 90Sr activity still remaining in the soil profile was found in the surface layer, but the relative amount decreased with increasing level of industrial pollution. Expression level of Wnt signaling components possibly influences the biological behavior of colorectal cancer in different age groups. The structure enables modelling of the docking interactions to its ligands, for example from focal adhesion kinase, and supports structure-based drug design of inhibitors of the CAS-FAK interaction. To differentiate between these events is required special skill, which is based on appropriate characterisation of the events (for example timing, repetition, pattern), the polysomnographic and video-EEG examination and validated questionnaires (FLEP scale).

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The Deauville 5-Point Scale Improves the Prognostic Value of Interim FDG PET/CT in Extranodal Natural Killer/T-Cell Lymphoma. The aim of this report was to report a rare case of bilateral periosteal osteoma involving the mandible--a painless, firm, and well-circumscribed lesion, with more bony prominence on the left than on the right side. The reaction of the pupil for light was checked in 25 patients with an unilateral retinal detachment.

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Do barbiturates in brain-dead organ donors have a deleterious effect on early renal graft function? Wounds were randomized to no treatment or topical OCA before and after full heparinization. A study has been made of epididymal resorption of spermatozoa in the field rat (Millardia meltada). Morphological evaluation indicated that PREP inhibition retarded the onset of differentiation. Significant advances in knowledge of the molecular genetics of brain tumors have occurred in the past decade, largely because of the availability of high-throughput profiling techniques, including new sequencing methodologies and multidimensional profiling by The Cancer Genome Atlas project.

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The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I. Despite efforts to reduce malaria morbidity and mortality, drug-resistant parasites continue to evade control strategies. The aim of this study was to determine whether a disposable thermometer was at least as accurate as a tympanic thermometer when compared with a mercury-in-glass thermometer and to investigate the waiting periods of mercury-in-glass thermometers. In order to develop such controls for studying cytokine mRNA expression in dogs, DNA sequence encoding a full-length canine HPRT protein has been obtained. Dechlorination was further confirmed by the chloride ion release.

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A volume-preset device for mechanical ventilation of infants and children. This classification is not arbitrary, as it correlates with other measures of development, and the epidemiologic patterns revealed show distinct differences, suggesting differing causes and intervention strategies. As a functional test, total coronary blood flow is a parameter with low sensitivity in characterizing patients with coronary artery disease and thus appears unsuitable in the selection of patients for medical or surgical treatment. The number of new herds tested per year and the proportion of new positive herds increased between 1994 and 1997. We show that several SL9 variants bind comparably well to soluble HLA-A2 and to a particular soluble TCR and that these variants are active in the cognate cytotoxicity assay.

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Reliable flaps can be raised from the fourth dorsal intermetacarpal space based solely on the distal recurrent branch, excluding the dorsal metacarpal artery and interosseous muscle fascia. This organelle is indispensable in providing adenosine triphosphate (ATP), a key effector of most biological processes. Ninety-three women aged 18-69 years were recruited from a previously formed cohort on the natural history of HPV to this cross-sectional measurement study. The overall success experienced with this novel application of HT sequencing of targeted regions suggests that the same approach could be successfully applied for SNP mining in other species.

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Or are they more apt to reinforce the dominant binary and hierarchical gender and sexual systems by appropriating gender displays and expressing sexual desires associated with traditional femininity and institutionalized heterosexuality? Results of this study might be useful in predicting actual recruiters at the outset of clinical trials. The excretion with rabbit milk has been investigated after subcutaneous administration of carbon-14 labelled amitriptyline and nortriptyline.

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Subjects were then required to make a visual match to the drawn forms. Endodontic management of hypo-, meso- and hypertaurodontism: case reports. Furthermore, CART-IR content and plasma CART-IR were significantly increased in adrenalectomized rats, and anterior pituitary CART mRNA expression, CART-IR content, and plasma CART-IR were significantly decreased in corticosterone-treated rats. Functional foods have evolved as food and nutrition science has advanced beyond the treatment of deficiency syndromes to reduction of disease risk. Following excisional biopsy, it was decided to retain the right maxillary canine and monitor its progress.

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Fifty CHR participants identified through the Structured Interview for Prodromal Syndromes and 52 age-/education-matched controls were assessed with a complete standard neuropsychological battery (the MCCB, MATRICS Consensus Cognitive Battery) and a social cognition assessment (Faux Pas Test, FPT). The school setting presents a unique public health opportunity to enact change on a variety of levels.

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Evaluation of experimental cartilage lesions with ultrahigh-resolution multi-slice-CT in comparison to histology Instead, they should only be considered in combination with established treatments or be attempted when these have not been successful. Supramolecular chemistry on water--towards self-assembling molecular electronic circuitry. Tennis elbow is a common and difficult-to-treat condition largely because of lack of evidence.

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The Task Force used consistent language and graphical descriptions of both the strength of recommendation and the quality of evidence, using the recommendations of the Grading of Recommendations, Assessment, Development, and Evaluation group. The strains were isolated from Egretta alba and Ardea cinerea, and Phalacracorax carbo in the Astrakhan region and from Lunda cirrhata and Uria aalge in the Komandorskie Islands. Comparative effects of two oral appliances on upper airway structure in obstructive sleep apnea. The most potent compounds show below 10 nanomolar activity towards wild-type HIV-1 and variants bearing Tyr181Cys and Lys103Asn/Tyr181Cys resistance mutations. Six point mutations in non-muscle gamma-actin at the DFNA20/26 locus cause autosomal dominant nonsyndromic hearing loss.

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The virological response to four consecutive therapies was evaluated in the Swiss HIV Cohort. There is good correlation in the results given by these methods. A large body of information suggests NSAIDS have a negative impact on the healing of bone. Thirty-nine eligible patients with ovarian carcinoma persistent, progressive, or recurrent after initial treatment with paclitaxel 200 mg/m(2) over 24 h every 3 weeks received cisplatin 100 mg/m(2) every 3 weeks until disease progression or unacceptable toxicity. Evidence-based mental health and psychosocial support in humanitarian settings: gaps and opportunities.

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Stricture-plasty for tubercular strictures of the gastro-intestinal tract. It has several causes and a wide range of clinical manifestations, from mild tachycardia up to multiple organ failure. We interpret this shift as a sign of maturation of evaluation research in medical informatics. An enzyme forming vasodilator polypeptides in human cerebrospinal fluid.

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Spirometry and peak expiratory flow in the primary care management of COPD. Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients AMA-negative PBC patients are characterized by relatively lower levels of serum IgM and a higher prevalence of serum ANA/SMA and are not associated with substantial differences in the clinical biochemical and histological spectrum of the disease. Our study suggests that rapid evolution plays a smaller role in the ecological dynamics of communities dominated by resource pulses. Intermediate-risk prostate cancer (PCa) represents a heterogeneous disease, where a non-negligible proportion of patients harbor favorable pathologic characteristics and are potentially eligible for active surveillance (AS).

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This article presents a novel closed loop control architecture based on audio channels of several types of computing devices, such as mobile phones and tablet computers, but not restricted to them. However, few studies have provided a comprehensive picture of the spatial and seasonal variability of metal concentration, solubility and size distribution, all of which have important roles in their contribution to health effects.

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Several studies have used the Fluorosis Risk Index (FRI) to assess risk factors for dental fluorosis. Lid lesions, which include calcified deposits adjacent to the meibomian gland orifices, are much less common. Advances in the understanding of anterior instability of the shoulder. Hospitalized adults at 14 hospitals with comprehensive inpatient EMRs.

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Addressing the Accreditation Council for Graduate Medical Education competencies: an opportunity to impact medical education and patient care. The expression of surface membrane glycoprotein (GP) Ib-IX complex, GPIIb-IIIa complex and CD62P (P-selectin) was examined by flow cytometry using fluorescence labelled monoclonal antibodies. Phosphorylation gradually decreases the binding affinity for dsDNA. Effect of euphyllin on the urinary excretion of water and electrolytes in patients with circulatory insufficiency

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We performed a case-control study of 354 breast cancer cases and 364 controls. In this study, simultaneous measurements of pressure and volume, in addition to a static study, were performed in vitro using four PA catheters (Abbott Opticath, Arrow Hands-Off, Baxter Edwards and Spectramed). This study is designed with a more appropriate model and investigates the effects of radiation after three common nerve injury paradigms.

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Here, we review the current knowledge regarding apolipoprotein B (apoB) metabolism, focusing on selected clinically relevant conditions. The present study showed that in Alzheimer disease (AD) neuropil, brain spectrin immunoreactivity is co-localized with synaptophysin in the presynaptic boutons. All angiographic phases were identified and time sequences were recorded.

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We already know that in a great number of these mechanisms, altered gene function is involved. Spondyloarthropathies: new directions in etiopathogenesis, diagnosis and treatment. In a small randomized study, 60 cava catheters were individually examined bacteriologically.

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